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drp 1  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology drp 1
    The results of western blotting (A) . The protein levels of PGC-1α (B) <t>and</t> <t>Drp-1</t> (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
    Drp 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 649 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+drp+1/DRP1+Antibody/pmc12900325-55-11-22
    Average 96 stars, based on 649 article reviews
    drp 1 - by Bioz Stars, 2026-10
    96/100 stars

    Images

    1) Product Images from "Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study"

    Article Title: Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

    Journal: PLOS One

    doi: 10.1371/journal.pone.0336221

    The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
    Figure Legend Snippet: The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.

    Techniques Used: Western Blot, Control

    Related Articles

    other:

    Article Title: Rosmarinic Acid: A Naturally Occurring Plant Based Agent Prevents Impaired Mitochondrial Dynamics and Apoptosis in Ultraviolet-B-Irradiated Human Skin Cells.
    Article Snippet: Ultraviolet B (UVB) radiation is the leading cause of premature skin aging and skin cancer.. UVB mediated mitochondrial dysfunction has been identified as one of the causative factors of UVB induced oxidative imbalance and apoptosis.. Here, we report that UVB leads to mitochondrial fragmentation by causing imbalance in the markers regulating mitochondrial dynamics, which further contributes to ROS imbalance and activation of mitochondrial apoptotic signals.

    Article Title: Baicalin Improves Skeletal Muscle Atrophy by Attenuating DRP-1-Mediated Mitochondrial Fission in Aged Mice
    Article Snippet: The following antibodies were used: anti-myostatin (MSTN) (ab203076, Abcam, USA); anti-muscle RING-finger protein-1 (MuRF-1) (sc-398608, Santa Cruz Biotechnology, Dallas, TX, USA); anti-atrogin-1 (sc-166806, Santa Cruz Biotechnology); anti-optic atrophy 1 (OPA-1) (612606, BD Biosciences, San Jose, CA, USA); anti-tumor necrosis factor α (TNF-α) (sc-12744, Santa Cruz Biotechnology, Dallas, TX, USA); anti-interleukin-6 (IL-6) (sc-57315, Santa Cruz Biotechnology, Dallas, TX, USA); anti-DRP-1 (sc-271583, Santa Cruz Biotechnology, Dallas, TX, USA); anti-apoptotic protease activating factor 1 (Apaf-1) (sc-65891, Santa Cruz Biotechnology, Dallas, TX, USA); anti-caspase 3 (14220S, Cell Signaling Tech, Danvers, MA, USA); and anti-GADPH (sc-47724, Santa Cruz Biotechnology).

    Article Title: A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca 2+ movement and extracellular Ca 2+ entry in skeletal muscle.
    Article Snippet: Anti-Drp-1, anti-Mfn1, anti-calcineurin and anti-CaMKII antibodies were obtained from Santa Cruz Biotechnology (Paso Robles, CA, U.S.A.). values in (c), (d,e) are presented as the mean ± s.e.m. for three independent experiments (Table 2).

    Article Title: Gambogic Acid Inhibits Gastric Cancer Cell Proliferation through Necroptosis
    Article Snippet: The antibodies used in the present study included anti-phospho-RIPK1 (Ser166) (Cell Signaling Technology, USA), RIPK1 (Cell Signaling Technology, USA), anti-phospho-RIPK3 (Ser227) (Abcam, USA), RIPK3 (Cell Signaling Technology, USA), anti-phospho-MLKL (Ser358) (Abcam, USA), anti-MLKL (Sigma, USA), anti-PGAM5 (Abcam, USA), anti-phospho-Drp-1 (S637) (Cell Signaling Technology, USA), anti-Drp-1 (Santa Cruz, USA), and anti-GAPDH (Santa Cruz, USA).

    Article Title: Exosomes from adipose‐derived mesenchymal stem cells alleviate liver ischaemia reperfusion injury subsequent to hepatectomy in rats by regulating mitochondrial dynamics and biogenesis
    Article Snippet: The primary antibodies used were the following: rabbit anti‐PGC‐1α (1:1000 dilution, wl02123, Wanlei); rabbit anti‐NRF1 (1:5000 dilution, ab175932, Abcam); rabbit anti‐TFAM (1:1000 dilution, ab252432, Abcam); rabbit anti‐MFN‐1 (1:1000 dilution, abs120025, absin); rabbit anti‐MFN‐2 (1:5000 dilution, ab124773, Abcam); rabbit anti‐OPA‐1 (1:3000 dilution, ab157457, Abcam); mouse anti‐DRP‐1 (1:500 dilution, sc‐271583, Santa Cruz); mouse anti‐Fis‐1 (1:500 dilution, sc‐376447, Santa Cruz); mouse anti‐Bax (1:500 dilution, sc‐23959, Santa Cruz); rabbit‐anti‐Bcl‐2 (1:500 dilution, wl01556, Wanlei) and rabbit anti‐β‐actin (1:5000 dilution, D110001, Sangon Biotech).

    Incubation:

    Article Title: Aerobic exercise timing affects mitochondrial dynamics and insulin resistance by regulating the circadian clock protein expression and NAD + -SIRT1-PPARα-MFN2 pathway in the skeletal muscle of high-fat-diet-induced diabetes mice.
    Article Snippet: Extended author information available on the last page of the article Abstract The circadian clock regulates mitochondrial function and affects time-dependent metabolic responses to exercise.. The present study aimed to determine the effects of aerobic exercise timing at the light-dark phase on the proteins expression of the circadian clock, mitochondrial dynamics, and, NAD+-SIRT1-PPARα axis in skeletal muscle of high-fat diet-induced diabetic mice.. In this experimental study, thirty male mice were randomly assigned into two groups based on time: the early light phase, ZT3, and the early dark phase, ZT15, and three groups at each time: (1) Healthy Control (HC), (2) Diabetic Control (DC), and (3) Diabetic + Exercise (DE).

    Article Title: L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson’s Disease
    Article Snippet: .. Proteins were transferred to polyvinylidene difluoride membranes and then blocked in skimmed milk for 1 h. The membranes were then incubated with: anti-cleaved caspase 9 (1:1000 Cell Signaling, Danvers, MA, USA); anti-p-JNK (1:500 Santa Cruz Biotechnology, Dallas, TX, USA); anti-p-AKT; anti-PI3K; anti-p-Bcl2 (1:1000 Cell Signaling, Beverly, MS, USA); rabbit monoclonal anti-p-Creb (1:1000 Cell Signaling, USA); anti-mBDNF (Abcam, Cambridge, UK, 1:500); anti-p-TrkB (Abcam, UK, 1:1000); anti-p-Nrf2 (Abcam, UK, 1:2000); anti-Mn-Sod2 (ThermoFischer, Waltam, MA, USA, 1:2000); anti-Catalase (Rockland, USA, 1:1000); anti-Gpx (Abcam, UK, 1:1000); anti-GstP1 (ThermoScientific, USA, 1:1000); anti-HNE (Abcam, UK, 1:500); anti-Sirt1 (Abcam, UK, 1:500); anti-p-Foxo3a (Abcam, UK, 1:1000); anti-Msrb2 (Santa Cruz, USA, 1:500), anti-Drp-1 (Santa Cruz, USA, 1:500), anti-Opa-1 (Santa Cruz, USA, 1:500), and anti-Mfn1/2 (Abcam, UK, 1:500) at 4 °C overnight. ..



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    The results of western blotting (A) . The protein levels of PGC-1α (B) <t>and</t> <t>Drp-1</t> (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
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    The results of western blotting (A) . The protein levels of PGC-1α (B) <t>and</t> <t>Drp-1</t> (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
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    The results of western blotting (A) . The protein levels of PGC-1α (B) <t>and</t> <t>Drp-1</t> (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.
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    Image Search Results


    The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.

    Journal: PLOS One

    Article Title: Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

    doi: 10.1371/journal.pone.0336221

    Figure Lengend Snippet: The results of western blotting (A) . The protein levels of PGC-1α (B) and Drp-1 (C) were compared between the studied groups. β-actin was used as an internal control. Drp-1: Dynamin-related protein 1, ip: intraperitoneal, I/R: ischemia/reperfusion, PGC-1α: peroxisome proliferator-activated receptor-gamma coactivator, Rem: Remdesivir, sc: subcutaneous.

    Article Snippet: Monoclonal antibodies were against PGC-1α (ab54481, Abcam), NF-κB p65 (ab16502, Abcam), Drp-1 (sc-271583), ATF3 (sc-518032), p-p53 (sc-377553), p-p21 (sc-377569), and caspase-3 (sc-7272) (Santa Cruz Biotechnology, Inc).

    Techniques: Western Blot, Control